Thursday, October 17, 2024

King Cobra-Naja Naja

 

King Cobra-Naja Naja

This is not something to alarm you but to point out how man has neglected the use of cobra venom for therapeutic use.

In addition there is a paucity of knowledge how venom evolved in animals and how some animals are resistant the smaller doses of venom.
I teach that it is the venom that is produced in our body after the bite that kills us not the cobra venom (to illustrate the fact that cytotoxins have multitude of actions).
For example bradykinin that causes pain is the product of our own tissues.

Snake venom is a modified saliva and we really do not know whether these are produced in evolution for digestion of the prey or to immobilize or anesthetize (humane to the dying prey). None of the points I have raised have been addressed conclusively and potential for the use of the modified venom molecule for treatment of leukaemia or cancer cells or as antithrombotic activity have not been discussed in scientific journal adequately..
Why?
The answer is simple.
Once they discovered that antivenom as a cure, everybody forgot about the biological role and what system they act and why, when where and how they modify the homoeostatic mechanisms.
Moment the commercial activity of preparation of antivenom starts the scientific investigation of biological nature takes a back stage.
That is very unfortunate.
There lot we can learn from these cytotoxins.

Coming back to cobra (baby cobra-are as poisonous as the adult), I killed a young cobra with a ruler when I was as young as the tiny cobra who was under my bed.

When that little fellow made his hood and kissed the death I fell heroic and also very sad.
Then in another incident when I jumped over huge cobra in a big compound and looked around to see he was as frighted as I was and showed his hood with a warning and quietly slipped away to his safety, I wondered why fear an animal who is on his routine search of his food or prey.

I still say the jumped I made that day worth an Olympic record if somebody made an accurate measure on that day. Unfortunately I missed an Olympic record since officials were not there to record it. That would have changed my life completely but the day that completely changed my mind was another ordinary day.
I was walking along a stream with the intention of catching guppies and I had a stone in my hand (we used to play marbles those days unlike today’s kids) and I saw a water snake (harmless creature) quickly swimming across in fear.

I took an aim in a moment of irresponsible stroke of mind of ill will and thought, threw the stone at the poor creature and it landed right on his neck.

It was like a bulls eye shot but the agony of the creature who succumbed in a long drawn out 5 minutes of death dance made an impact in my mind never to hurt (reflecting my killing in fear of the young cobra) an animal in either fear or sport.

Then on one night (2 am in the morning) in darkness a Ceylon krait landed on my right shoulder and I brushed it with my left hand gently and put the light in a flash to see creature landing on cement flow with a thud and my dog charging at it, I was man thinking of three lives my dog, myself and the poor creature who ventured at night.
Mind you Ceylon krait is the deadliest of Sri-Lankan venomous snakes.

I watched the creature and it quickly disappeared into crevice wide open due to rotten timber of the bathroom door.

I did not have any cement to seal and went to the kitchen an took some American flour (who says American flour has no place in this country) and sealed the hole with the dough hastily made since the price of flour was very cheap (cheaper than the cement) then.

Suffice is to say I flushed the hole with water before I did that and slept on the settee fearing few more in my bedroom.

After three days it emerged (none elsewhere) from the kitchen floor cracked and we caught it and released it to safety.

Of course I had to cement both holes in the bathroom end and the kitchen end.

The key point here is that animals fear us more than we fear them in this modern world where are we are encroaching on their habitat with blatant disregard to biodiversity.

Brain Myths, the Malady of Democracy

Reproduction
Brain Myths, the Malady of Democracy
There are a lot of myths spread by Psychologists.
This is an attempt to bring some sense and reality into day to day life.
I may dispute many a myths but my attempts are also not infallible in each and every situation, one may encounter.

Making right or correct decision at a given moment is a knack which many of us lack.

If we delay acting on a given (it may be right or it may be wrong) problem even for a fraction of a second, the most destructive procrastination sets in.

Then any given solution is the base for next round of further procrastination.

But if we keep an open mind and believe in what we intend to do given a difficult problem or a preposition, the solving of the problem may come naturally, to anyone.

This is not easy, though.
Lot of training actually hinder this ability.
That is what we call common sense.
Lot of experience also may be a hindrance.
Basically we have several approaches to a given problem.

Just think of a Game (Video game)
One’s approach may be (not comprehensive here)
1. Offensive
2. Defensive
3. Neutral
4. Random or Calculated Response 
5. Cool (not procrastination)

The best approach is the last which has all the above components assessed in a fraction of a second

Only a few has that cool talent.
They are ones who become successful.
The COOL people are actually very observant.

But many of us use the useless procrastination approach (usual approach of a politician).
What it does is to kill the attempt at solving a given problem from the very beginning.
Unfortunately many of us use this method since we do not believe that some problems can be addressed, if we care to divert from the common approach.

This is what Professor De Bono calls Lateral Thinking.
It is not vertical or analytical or direct thinking.

Side track a bit,
Focus on the problem,
Leave behind the past experiences for a moment,
Give attention to the present moment of time
Then in a FLASH
A new found solution springs up.

Then if we have few others with equal interest and talent get involved in the same problem we get endless stream of solutions which we have never thought of because of the redundant past experience.

We call it brain storming and it really works.

If one does not use common sense what I say here is superfluous.
We use our past experience to solve a given problem.
Sometime past experience is useful.
Sometimes past experience is a hindrance.

Past experience is sometimes a hindrance to creative and pragmatic solutions.

Good example can be taken from politicians.
When somebody is opposition for a long period of time and then come to power, he / she makes many mistakes due to past misfortunes.

They have lost the ability for creative thinking.

Unfortunately this happens when one is power too, and they do not realize what a wonderful thing to be in opposition.

The people in the opposition see the problem realistically but they do not have the muscle to power the solution through.

It is the malady of the democracy.

Did you ever thought of, who would come to your funeral (Party)?

 Posted on

Did you ever thought of ,who would come to your funeral (Party)?

I have never given thought to this question but a reason observation have made me to sharpen my observation.

I will come to that later.

But rest assured all the following will be there at your funeral.

1. Almost all your enemies without any exception since they are happy to see you are out of sight. 
They of course like to see your loved one in distress.
This is similar to the God Father Story and one of its funerals and how the rivalry is taken up by the next of kins.

2. All your creditors (you have not settled your debts) will be there to see who are the next of kins to get back the money.

In this context your banker including the Central Bank representative will be there for sure.

3.  A monk, a priest, a rabbi, mullah even if you a  robber baron.
This is the only sure thing in this world.

4. All your neighbors come even though you have been there in the locality only during the last few months of your worldly stay. 
This is to make sure that any one of their kith and kin bid farewell at least the quorum (in numbers) is satisfied in the next funeral.

5. Your local politician will come but because now there are no local representation the number has diminished.

In any case, you are dead now there is no more of your vote left.

Why the hell one should attend?

The 6 and 10 of the list are your supposed to be friends (but many of them will find an excuse not to come).

Real Story
Now to the story which I should bare free now that the 3 months Dhana Ceremony was over.
This was the funeral of a don who had passed away.

He was one of my teachers.

I had close association with him when alive.
There was no official representative from the university, even though like a fool he left his village and come to live near the academic environment.
This was a pity.

What was shocking was none of his children came who were supposed to be professional.

It is no point having  doctorate or PhD, if simple ethics are forgotten for good.

The bottom line is if there are many in one’s funeral most of them are one’s worthwhile enemies and please don’t look down from heaven and count the numbers.

Ten (10) Plus points about Linux Distributions when in USE

 Reproduction

Sunday, February 20, 2011

 Ten (10) Plus points about Linux Distributions when in Use

It is time I should write some important things about Linux that you may not read in books but only experience with regular use.

Even though most of the proprietary guys do not provide the necessary drivers for Linux or support Linux, the modules that are used in new kernels are robust and reliable and never fail. 
They look after the hardware without breaking them down even if you use the system 24 /7 schedule unlike Microsoft counterparts.

Linux kernel is made to run 24 / 7 schedule without braking down (except normal maintenance). 
The maintenance jobs are done in the early hours of the day (they are called CRON Jobs) when system is not in use but with idling with power on. One of the biggest mistakes Linux newbies do is to switch off the computer in the night. Unfortunately running 24 hours is not practiced in our university setup since by evening and over weekends servers are switched off and junk that should have been removed automatically get collected, overnight and over the weekend.

1.One is able to run your computer 24 / 7 schedule is its strongest point and its strength.  
No need for restarts every time a minor configuration change is made unlike in windows. These changes are done in real time and no delay is contemplated, the moment a command is activated.

2. Linux look after the time scheduling to nanoseconds. 
For example if one is using K-torrents for downloading several files, it shares time allotment with the files. Faster files get a bigger share and slower files get a smaller share and the full band width is used. One can limit the upload and download speeds if it is used in a network.

3. Looks after the hardware and the processor well and if there are problems they are reported at boot time (one should be able to read these messages at boot time which are displaced for a fraction of a second). Once a major problem is detected the Linux has the canny habit of switching off instantaneously.

Once after a lightening and power outage (it ran through even the UPS battery) one of my computers had some electrical burns. They system never ran more than few seconds after this power outage, not even for me to read the boot menu. Only, after three days, I realized the problem but it had been telling me that the cooling had gone wrong on the first few seconds which I was not able to read fast enough. This problem was solved with the help of a young guy but I was all the time thinking of a boot virus since I fixed a second hand SATA hard disk 3 days before to up the capacity. 
Linux boot and grub file have a good warning systems, if one is careful to read them at boot time.

Not only that Linux is a work horse it looks after minor injuries to the horse.

4. What I really like about Linux is it looks after CD ROMs and CD/DVD writers well. It usually run on default setup but at write time it tests both the CD/DVD and uses the best and safe formula and writes the job in incremental or decremental speed. It does not start writing even if there is a minor fault in the CD or DVD.       It does not do a job blindly, it assesses the process and resources even to mini seconds.

5. It is really a multitasking Operating System unlike Windows and work with other computers in a network and synchronize work.

6. It is multi-user operating system (Ubuntu lacks this due to changes to the desktop system and that is one of my reasons not favouring it in spite of the wider user experience). 
It is always runs on root and never lets one to use a user account.
I do not use Ubuntu at all except testing its new versions. 
I won't waste my time testing its 12.10 version.

7. It records (keeps a history) and everything is measured to nanoseconds.

8. It uses RAM efficiently and when things are not favorable uses SWAP partition (not swap file as in Windows) to swap files and data. This is why it is much efficient than Windows.

9. It is secure from attack if the firewall is properly configured and it is almost free of viruses.

10. It keeps everything in a designated place and file structure is stable even though rigid and your data is in (need to be partitioned accordingly) a /home partition. I can upgrade or reinstall the system without any changes to the /home (data) partition. 
That was one reason I really liked it when I was testing many distributions in the early days of my Linux adventure.

I have never lost a file for 10 years. Would you believe it. Only problem is now I am short of short term memory and I forget with what name I have named the file. 
I have downloaded over two (200) hundred images and made mistakes in only 3 out of the fist 100 and nothing after that. It is almost zero after I started using K-torrent. I used PCLinux in my early days including Big Daddy.
I currently use Transmission of (Gnome) Debian.

If you want a work horse to do your jobs. It is always Linux.

Education, Teaching and Learning

I may write a book on these three topics but only when I run short of ideas to Write.

I am a high IQ guy.
That is the assessment of my fellow classmates.
I had high memory capacity which is gradually failing due to old age. 
Does not bother me and what remains is good enough to take me to 80 but I wish to kick the bucket, the moment my memory fails.

I do not carry a cellphone or store information in the cellphone.
On a few rare occasions, especially when traveling abroad, I carry a tiny notebook.

In my retirement, I do not set tasks but during my working years, I finish all my work by 12PM and thereafter, test all the New Linux Distributions (post a mini review) and test a few of their running utilities.

My current obsession is to make Linux PC penetration 10% and it is around 4% currently.

I thought that all my classmates had the same IQ capacity as me BUT they were Lazy.
I am proven wrong. 
We have different capacities and the education should cater for the Slow Learners not the Fast Learners like me.

This piece is about me.
Teachers who assessed me, in my primitive years did not tell me my potential (Good on them) but said I was a bright cookie.

By the way, I was good in athletics.

1. I went to missionary school first.
There they tried to convert me to Christianity which I strongly opposed and I was thrown out of the class as a punishment.

2. I schemed and got all my Buddhist mates out of the class in one week.
I was a rebellious but was Not a JVP activist.

I was against all indoctrination.

3. When things started getting hot I stopped going to school.
I told my father, find me a school in the city.

4. He went to all the schools in Kandy and they all refused me having looked at my record book which was pretty good.
I was happy.

5. I did not take this plunge (stop going to school) lightly. 
There was another reason, related to making the boys school, a mix school due to government intervention.

6. During school last athletic meeting, the visiting principal of the city school while handing over Under 14 Championship Cup to me, he whispered to my ear, if you want to come to my school, come and see me.

7. I was head of Junior Cadetting team.
I hated scouting for many reasons.

8. I was forced to do Senior Cadetting in the city school. 
I came there to do real schooling not Cadetting. 
So every time I was taken in, I used spoil the march past, deliberately.
I was thrashed with Albesia Stick until it broke in to several pieces. 
I stood firm until I was thrown out of the "scoud".
He was the Vice Principle. 

9. By this time, I started hating all the teachers. 
We had a terrible set of science teachers.

10. We had a plot. 
Only six of them were in the plot.
I was leading the team.
Three of them have left us only 3 left now.
I managed to collate information of our classmates before, I left Ceylon.
Coronavirus episode curtailed and ended the proposed gathering.
I avoid the "Big Match" which is a "Houch Party".
I stopped my drinking habits after publishing the book "Joys of Alcohol".
The topic was selected to encourage sales but it gives all, "Good, Bad and the Ugly" in the tradition of the Western Film.

11. I went and met the Vice Principle who thrashed me and told him we were very badly treated by the teachers that we wish to stay out of the class. 
Please give us six chairs and place them next to the library. 
We will not spoil the learning of the students left in the class.
We gave him the undertaking that all of us will enter the University first time round.
Our negotiation succeeded. 
We all entered the University and none left in the class did.

12. The school library was hopeless.
But British Council Library had all the books we needed.
Six of us borrowed the books we needed and shared them in school.
I took classes for my mates in chemistry and physics.
I was very good in physics but did decided to take medicine for higher studies. 
If I did physics, I knew I become a loner.
I must make a note about the School Inspector Mr. Panamaldeniya. 
I reported to him all what was happening in the school including my class teacher not allowing me to apply for medicine. 
He sorted this out for me.
Then we had a teacher from Galle named Mr. Widyasekara who was on teacher training assignment in our school. We got him to teach chemistry.
The teacher who refused me signing me for medicine sited that I had not done enough "Organic Chemistry" practicals. 
I argued that practicals are after Theory Examination and I would do them during the school holidays. 
The chemistry lab was completely neglected.
Sure enough, 6 of us cleaned up the entire chemistry laboratory, including preparation of chemicals necessary for tests, including titrations.
 It did not help me.
I got a chemical (naphthalene or para- dichlorobenzene or moth ball) which was non reactive after repeating the test.
I wrote this may be naphthalene or para- dichlorobenzene.

Additionally, I got another teacher to guide me on organic chemistry practicals.
He was a chemistry special guy (Mr. Samaranayake) waiting for an appointment outside schools.
 
Sure enough,, two of the six ended up in Chemistry Special. 
All 25 students were suspended for life for cheating in the Final Examination except two of my friends, who did not cheat. 
Both are no more.
One of those guys who copied ended up as a MP.
All the others ended up as lawyers but I never saw any of them.
Any cheat including politicians can enter Law College.

13. We had very bad medical teachers.
Professor Senaka Bible was an exception.
One day, I met my supervisor and I told her I am going home and not coming back.
I said, if beginning of the career is this bad end must be even worse.
She was taken aback and made an appointment for a proper sit down with the professor. The problem was solved amicably and we decided not to divulge what was discussed.
Incidentally, I scored highest in that subject and they called me to tell me that fact. 
They were in two minds whether to award a distinction. 
I said please do not.
I do not deserve it.
At this point, I must say, my relationship with my father.
He discouraged me and told me not to do medicine. Before we entered there was a paper advertisement to offer a scholarship.
It had a strange request. I would get it only if I decide to do science instead of medicine.
I said NO.
Second, I requested him to buy a book on anatomy (it was not available in the library and the British Council Library). 
It was very expensive.
He told me, he almost had a heart attack.
I told him this is the first and the last time and I will repay it in good, later.
I solved all his financial problems within a short time.
I decided never to buy any medical books as a student and used only library books.
 
Of course, I bought many medical books after graduation.
I bought two copies of General Pathology by Water and Israel. I thought the second copy was a recent edition but it wasn't.
That book had been on my bedside all my life.
It really does not need any updates.

Solid and Scientific.

14. Jealousy was at its peak. 
One of the guys in the class stole two of the very expensive books that I borrowed from the British Council Library. 
His name is Sangakkara who came from Kurunegala. 
I hate all Sangakkaras, including one who was MS in Kandy Hospital.

There were many other petty incidents. 
We reported all of them to the class teacher but no action taken.

15. I paid money for the lost books to the British Council Library on a concessionary rate. 
Luckily for me the assistant librarian was an old boy form the city school. 
It lead to a prolonged and healthy relationship with the library. 
I had a scheme to catch people who steal books from this library.
I would buy any book for RS.100/=.
I returned the book with the guys name and his membership was cancelled and he is not allowed to sit even in the reading room. 
When the third guy was caught the stealing episodes went to the acceptable level.

I must tell you there was two clinical professors (of my time) from the University who used to steal books from the Medical  Library. 
One is dead and the other, I had a very heated exchange (he left the University) over distortion of Buddha Dhamma
I told him Dhamma is not his field of expertise and leave it to the erudite.

My experience abroad is that Indians are the worst of all, stealing books. 
They start tearing pages from books to begin with and finally the entire reference collection is lost.

Beware.

16. For this help I was given the books I needed before they were accessed and put in to circulation, all throughout my University years. 

I never lost a book but never took them away from our home, fear of losing them.

17. I have over 1000 books, most of them are on Linux. 
They are gathering dust. 
I spread them with gasoline (thinner plus moth balls) type of liquid our "mason bass" Navaratne prepared to kill book worms (silver fish, book-lice and termites), before l left Ceylon.

I have lost several books having loaned them to my cohorts. 
One of them was the Geneva Convention on Human Rights, which I obtained with difficulty. 
This guy died of a cancer and I told him he should seek medical advice.
I picked up the early signs of cancer in him. 
Neither he believed me  nor listen to me.
Of course, I was not in Ceylon when he was finally diagnosed with bladder cancer which is very aggressive.

18. All post graduate degrees and PhD awarded belonged to the Institution that awards them.
They are not personal items to wear.
In my case, I did the basic stuff at the age 60 and kept the substantial stuff for myself to publish books with data, so I can make Royalties
One cannot make Royalties from the PhD.

As for my Medical Registration, I refused to pay money every year to Medical Council from the year 2000 onward, since I do not dispense any medicine to any guy or girl. 
I pretend to be a PhD doctor, not a medical one for the last 24 years.
That gives me freedom to voice my opinion, including medical stuff.
 
This come good for me. I published a book "Coronavirus who cheated us, Locally and Globally" . 
I was critical of Doctors (Andrew Fousi to begin with) and WHO who handled it poorly.
It is selling well in America.
I was critical of our regime but without data I did not mention guys and girls who made a profit on the side.
 
Now to the crunch points.
 
1. I do not like indoctrination of JVP style.

2. Learning is more important than teaching. 
I did not enjoy teaching.
Retirement was a blessing and guys wanted spoon feeding.
Guys come to the University and they could not define the word definition.

3. I hate free school books.

4. I encourage only English books.
I could not find a copy of Das Capital by Carl Marx. 
I am still looking for it.
 
5. Learning a second language makes one creative. 
Single language guys are not good even in politics.

6. One can learn a new language during the critical period of 7 to 16 years.

7. I passed French 'O' Level at the age of 55. 
But I am not proficient enough, yet.
I have decided not to visit Paris until Macron is evicted.

8. Learning is a life long endeavor.
This is what I learned from late Sir John Kotalawala
He was one of my last patients in Ceylon. 
Reverend Narada Thera was teacher cum patient. Both left us when I was abroad.

My first clinical (Dr. Drahaman) teacher (not under my care) was struggling for life at Navaloka Hospital. 
He could not recognize me. 
That is how life events unfold.

By the way, I signed the last blood report of JRJ (our late President) , and said this guy cannot be living.
The osmolality of the specimen was well below resuscitation level or in other words cerebral oedema and Brain Dead.
Report went out at 12PM.
I do not know who signed the Death Certificate.
 
They were hoisting white flags when I passed Ragama by train that evening at around 4PM.
Reverend Renukane Chandhawilama Thera was in coma right at the same time.
I did not who he was but bought a few of his books in Sinhala.
I believe they should be translated to English.
 
 For me, The Dhammapada by Reverend Narada is my pick.

I have quite a number of books on Buddhism published at Amazon Books and two books on Ceylon and its Rivers and Water Falls.
 
By the way, I was involved in "Total Quality Management Training" at Navaloka. 
Part of the work was to develop hospital wide "Network  Connectivity" (first time in Ceylon) using Unix. 
We trained 8 guys and few of them were sent to Singapore for training.
Navaloka received the Quality Award for that year. 
I joined the University after 7 months but continued to visit over weekend to finish the Quality Training Proposal.
20 years later when I visited there for VISA formality for my son, two out of three of us did not have chairs to sit.
That is the End of Quality Training in Private Hospitals in Ceylon including Asiri Hospital.

9. My current learning topic is Philosophy.
Philosophy is the First Order discipline.
All the others including religion are Second Order disciplines.
 
10. Thinking to Think is  the most important part in learning.
Read books by Professor De Bono, who is no more.
I have quite a number of books by him including Beautiful Mind and Wisdom Thoughts.
My teacher of Philosophy was late Professor A,D.P Kalansuriya.
In his retirement he did not have money for the the battery of the pace maker.
He never told me about his medical problems. 
He was down to earth man philosophically speaking, and he was ready say "Good Bye" when his daughter was given in marriage.
 He taught what is called Language Games in Philosophy.
 
I have not given up on philosophy.
 
11. Our education system is in ruins including in the Universities.
In my belief, it takes another 20 years to get us back to "Global Needs".

Developing Private schools is not a solution but adds another dimension to the already existing problem of ever expanding curriculum.

Ranil Wickramasinghe's plan was to destroy "Free Education" apart from creating Batalanda Training School.