Basic Intel NUC can be booted with USB.
One need not have an expensive Hard Disk.
Basic NUC consumes very Little Electricity.
If you boot it with a USB (not a Live Session) in which Debian 12.4.0. Live DVD Installed as a proper installation, USB can be removed.
NUC won't boot without the USB so both the NUC and USB are safe.
Since one uses a password fro booting even if you misplace the USB one cannot steal it.
The advantage is one can store data and file as a normal hard drive.
In a Live Session unless the Distribution supports persistence Like Knoppix one cannot store data.
Puppy Linux of course save data, which it reserves from the Hard Disk. The USB should be at least 32GB capacity and 64GB USB is ideal for safty and for your pocket.
Buying a big Hard disk is a wastage of money and in addition consumes lot of Electricity and Heat Energy.
It is good for planet!