Monday, July 31, 2023

Achievements

1. Linux was my single most achievement.

This Freedom from Apple and Microsoft was achieved singlehandedly by shear perseverance.

There were no Gurus except the Linux Bible.
When I started there were only 32 in the entire world using Linux in a PC.
Now it has gone up to 3% users.

2. Listening to bird songs is my pastime.

In Ceylon there are about 30 different bird songs starting at 5AM and finishing at 5PM.

Some of them are very secretive and I know of their existence by their particular song.

3. Communicating with an alien before my demise is my only unfinished job.

I want to tell them do not come here guys.
We are still Zero Level Civilisation.

4. I have to finish few more books.
One is about Global Truth Embargo.

5. I was born after the World War II.
My only wish was never to see the World War III.

6. I hate AI telling me it is time to Wake up or Sleep.

7. I wish the digital data I have left behind including Coronavirus Saga is left behind for another 5000 years (probably my guesstimate of birth of a new civilisation).

8. I have not found a clue to why in cell culture media and in biological studies Cell Division is restricted to 50 Cell Cycles in total.
We know that when cell cycle goes out of step it leads to cancer and leukaemia.

Why it is 50?

Why can't it be 120 or 300?
I am going to die with this puzzle.

This is called Haylick number.

I just listened to a guy named Rupert Sheldrake who has studied this phenomenon from 1970 and has postulated a theory.

He call it asymmetric cell division where the mother cell accumulates the errors (unable to repair) but the daughter cell remains young (able to rejuvenate) with minimum of errors.
Stem cells that are not differentiated have this property.
But there is a complication every time a cell divide the telomeres shorten until the cell lose it ability to divide. 
They DNA also accumulate methylated segments that add to the problem.

In the case of Hela Cells (grown in cell culture from a cervical cancer) the potential for cell division is endless.
The embryonic cells have the potential for endless division but as the embryo grows this potential is lost and subsequent cells start aging.
These are called oncogenes that some viruses hijack for vital cell division, especially DNA viruses.

His theory is the cancer cell can excrete damaged components including DNA/RNA segments by a mechanism found early embryonic cells.

I believe in other worlds or alien worlds there is no tight restriction at fifty cell cycles and they live very long lives.

That is the only valid reason to propose that alien visitors may have manipulated our Cell Cycle to a finite of  50 so that population is controlled at 7 to 9 billions.

? ? ? Beyond that point it is  catastrophy for this planet.


No comments:

Post a Comment