Thursday, April 9, 2020

Tuberculosis and BCG vaccination.


Tuberculosis and BCG vaccination.

My advice as a pathologist is that the TB vaccination (BCG) should be given at birth.

Furthermore, Mantoux test should be done before adolescent are vaccinated.

There were only two in our class (I was one and the other was Donald, Jaffna Tamil, my best friend) who were Mantoux negative out of over 50).

Only two of us got the BCG vaccination.


In other word 95% were exposed to TB as a Child (they should not be vaccinated to avoid reactivation of OLD TB).

This is true in India and Africa.

Then there is also Atypical or Anonymous Tuberculosis (PHD thesis of one of my teachers was not validated by the crooked supervising committee.in Peradeniya, fearing one may not get a chance to go abroad for higher studies).

Local degrees were considered inferior.
 
So annoyed my teacher gave up local research and ended up in Australia as a GP.

He had five children and all of them are doing well in many fields abroad.

So I decided to do my research in this country well past 50 yeas (my thesis) and part of the good quality data, I never gave to the University but used as my base for three books published at Amazon.)

By the way, I used five times the university contribution from my own pocket.
The money allocated was meager.

Coming to TB vaccination (polybacterial and polyvalent) as a whole there are lot of antigenic particles that activate lymphocytes and later taken up by the macrophages for intracellular digestion.

What it signals is that the macrophage has a nonspcific receptor on its surface to bind coated Coronavirus (not RNA particles).

One should identify this receptor in any new protocol.